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Marginal GWAS statistics for continuous trait

Source: R/simulate.R
get_marginal_stats.Rd

Calculates per-SNP marginal effect sizes and Z-scores via ordinary least squares (OLS).

Usage

get_marginal_stats(X, y)

Arguments

X

Numeric matrix. Genotypic dosage matrix (individuals x SNPs).

y

Numeric vector. Continuous phenotype vector.

Value

List with two elements:

  • beta: Marginal effect sizes.

  • z: Marginal Z-scores (non-finite values set to 0).