Auto-detects common column schemas (CNCR/Savage, PGC, GCST). Derives Z from
beta/SE, or from P and effect sign when Z is absent. Handles files with or
without an Effect Allele Frequency (EAF) column.
Usage
read_sumstats(path, chr = NULL, start_bp = NULL, end_bp = NULL)
Arguments
- path
Path to (optionally gzipped) delimited sumstat file.
- chr
Optional chromosome to subset.
- start_bp, end_bp
Optional base-pair window.
Value
A data.table with standardized columns: snp, chr, bp, a1, a2, z, beta, eaf.